Recruitment of Jub by α-catenin promotes Yki activity and Drosophila wing growth
نویسندگان
چکیده
منابع مشابه
Cytoskeletal Tension Inhibits Hippo Signaling through an Ajuba-Warts Complex
Mechanical forces have been proposed to modulate organ growth, but a molecular mechanism that links them to growth regulation in vivo has been lacking. We report that increasing tension within the cytoskeleton increases Drosophila wing growth, whereas decreasing cytoskeletal tension decreases wing growth. These changes in growth can be accounted for by changes in the activity of Yorkie, a trans...
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Dexing Fang, David Hawke, Yanhua Zheng, Yan Xia, Jill Meisenhelder, Heinz Nika, Gordon B. Mills , Ryuji Kobayashi, Tony Hunter, and Zhimin Lu** From the Brain Tumor Center and Department of Neuro-Oncology, Department of Molecular Pathology, Department of Systems Biology, **Department of Molecular Genetics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, the The Univer...
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The gradient of Decapentaplegic (Dpp) in the Drosophila wing has served as a paradigm to characterize the role of morphogens in regulating patterning. However, the role of this gradient in regulating tissue size is a topic of intense debate as proliferative growth is homogenous. Here, we combined the Gal4/UAS system and a temperature-sensitive Gal80 molecule to induce RNAi-mediated depletion of...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2019
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.222018